The White House further said that US athletes could attend and would have the government's full support.
China has previously said it will take "resolute countermeasures" in the event of a boycott.
President Joe Biden said last month that he was weighing up a diplomatic boycott of the winter olympics, the report said.
White House press secretary Jen Psaki confirmed the boycott on Monday, saying that the administration would not contribute to the "fanfare" of the Olympics.
"US diplomatic or official representation would treat these games as business as usual in the face of the PRC's [People's Republic of China] egregious human rights abuses and atrocities in Xinjiang," she said. "We simply can't do that."
Ms Psaki added that the US government did not feel "it was the right step to penalise athletes who had been training for this moment", but that not sending an official US delegation to the 2022 Games "could send a clear message".